惗懱婡峔妛暘栰嫗搒戝妛戝妛堾擾妛尋媶壢墳梡惗暔壢妛愱峌

Laboratory of Animal Physiology and Functional Anatomy


尋媶嬈愌

-奺嬈愌偐傜偺儕儞僋偵偼丄妛奜偐傜偺応崌丄墈棗偵惂尷偑偁傞応崌偑偁傝傑偡丅-
2010
溲扟寬堦丒扟岥幯栯丒郷栰婱巎丒扟峗丒摗揷夒旻丒懞忋尗巌丒抮揷弐懢榊丒彫憪孾曘丒嵅摗寬巎丒媣暷怴堦 (2017) 崟栄榓庬斏怋媿偺暘曍慜屻偺寣燋惉暘偵媦傏偡姡憞僯儞僕儞媼梌偺塭嬁
擏梡媿尋媶夛曬
103:38-42.


Ikeda S, Sugimoto M, Kume S (2017)
The RPMI-1640 vitamin mixture promotes bovine blastocyst development in vitro and downregulates gene expression of TXNIP with epigenetic modification of associated histones.
Journal of DOHaD Epub ahead of print.


Ikeda S, Kawahara-Miki R, Iwata H, Sugimoto M, Kume S (2017.6)
Role of methionine adenosyltransferase 2A in bovine preimplantation development and its associated genomic regions.
Sci. Rep. 7(1):3800.

嶃忋恀桪抮揷弐懢榊悪杮幚婭丒彫憪孾曘丒嵅摗寬巎丒媣暷怴堦 (2017)
斿擕儅僂僗偺彫挵偲擕態偵偍偗傞柶塽僌儘僽儕儞俙嶻惗偵媦傏偡姡憞僯儞僕儞偺塭嬁
娭惣抺嶻妛夛曬 174:10-16.


Nishijima Y, Taniguchi S, Ikeda S, Yoshitani K, Hamano T, Tani H, Fujita M, Murakami K, Kogusa K, Sato K, Sugimoto M, Kume S (2017.4)
Effects of 兝-carotene-enriched dry carrots on 兝-carotene status and colostral immunoglobulin in 兝-carotene-deficient Japanese Black cows.
Anim. Sci. J. 88(4):653-658.

媣暷怴堦 (2017)
兝亅僇儘僥儞傪妶梡偟偨崟栄榓庬巕媿偺幘昦梊杊偲挵娗柶塽夵慞
塰梴惗棟尋媶夛曬 61(1):1-8.


2010
嫶杮抦柧丒徏嶳撧墰丒悪杮幚婭丒抮揷弐懢榊丒媣暷怴堦
(2016)
棧擕巈儅僂僗偲斿擕儅僂僗偺IgA嶻惗偵媦傏偡儁僾僠僪垷墧偺塭嬁
旝検塰梴慺尋媶 33:59-62.


Okuma C, Ohta T, Ito M, Tadaki H, Oda T, Kume S, Nishiu J, Kakutani M (2016.2)

Intrajejunal infusion of 2-monoacylglycerol reduced food intake without inducing diarrhea in rats.
J. Pharmacol. Sci. 130(2):136-138.


Taniguchi S
, Wang M, Ikeda S, Yoshioka H, Nagase H, Kitamura S, Itoyama E, Murakami H, Sugimoto M, Kume S
(2016.4)
Relationships between immunoglobulin M and immunoglobulin G or A in colostrum of Japanese Black multiparous cows.

Anim. Sci. J.
87(4):536-540.


抮揷弐懢榊 (2016.2)
壠抺弶婜泱偵偍偗傞僯儏乕僩儕僄僺僕僃僱僥傿僋僗
-One-carbon metabolism 偺弶婜泱敪惗偵偍偗傞栶妱-
塰梴惗棟尋媶夛曬 60(1):1-11.


2010
愹扟幯栫壚丒悪杮幚婭丒抮揷弐懢榊丒媣暷怴堦 (2015)
棧擕屻儅僂僗偺彫挵偵偍偗傞IgA 嶻惗偵媦傏偡價僞儈儞C 偺塭嬁
旝検塰梴慺尋媶 32:63-66.


扟岥幯栯丒墹栔搶丒抮揷弐懢榊丒媑壀廏峷挿悾桽巑杒懞徦巕
巺嶳宐棟撧懞忋峅柧彫憪孾曘嵅摗寬巎丒悪杮幚婭丒媣暷怴堦 (2015)
崟栄榓庬斏怋媿偺弶擕拞柶塽僌儘僽儕儞娷検偵媦傏偡姡憞僯儞僕儞媼梌偺塭嬁

擔杮抺嶻妛夛曬 86(4):473-479.


庰堜崑懢丒慜揷壚桽丒悪杮幚婭丒抮揷弐懢榊丒栘懞堦夒丒媣暷怴堦 (2015)
斿擕儅僂僗偺擕態偵偍偗傞柶塽僌儘僽儕儞俙嶻惗偵媦傏偡僈儔僋僩僆儕僑摐偺塭嬁

擔杮抺嶻妛夛曬 86(3):319-324.


Kudo M, Ikeda S, Sugimoto M, Kume S (2015.12)
Methionine-dependent histone methylation at developmentally important gene loci in mouse preimplantation embryos.
J. Nutr. Biochem. 26(12):1664-1669.


Ishii Y, Motohashi Y, Muramatsu M, Katsuda Y, Miyajima K, Sasase T, Yamada T, Matsui T, Kume S, Ohta T (2015.8)
Female spontaneously diabetic Torii fatty rats develop nonalcoholic steatohepatitis-like hepatic lesions.

World J. Gastroenterol.
21:9067-9078.


Okuma C, Ohta T, Tadaki H, Hamada H, Oda T, Taniuchi H, Yamanaka K, Ishii Y, Ohe Y, Yata S, Nishiu J, Aratsu Y, Oshida S, Kume S, Kakutani M (2015.7)
JTP-103237, a novel monoacylglycerol acyltransferase inhibitor, modulates fat absorption and prevents diet-induced obesity.

Eur. J. Pharmacol.
758:72-81.


Okuma C, Ohta T, Tadaki H, Ishigure T, Sakata S, Taniuchi H, Sano R, Hamada H, Kume S, Nishiu J, Kakutani M (2015.7)
JTP-103237, a monoacylglycerol acyltransferase inhibitor, prevents fatty liver and suppresses both triglyceride synthesis and de novo lipogenesis.
J. Pharmacol. Sci. 128:150-157.


Katsuda Y, Sasase T, Tadaki H, Mera Y, Motohashi Y, Kemmochi Y, Toyoda K, Kakimoto K, Kume S, Ohta T (2015.5)
Contribution of hyperglycemia on diabetic complications in obese type 2 diabetic SDT fatty rats: effects of SGLT inhibitor phlorizin.
Exp. Anim. 64:161-169.


Wang M, Ikeda S, Yoshioka H, Nagase H, Kitamura S, Itoyama E, Murakami H, Sugimoto M, Kume S (2015.7)
Relationships between immunoglobulin and fat-soluble vitamins in colostrum of Japanese Black multiparous cows.

Anim. Sci. J.
86(7):673-678.


2010
Wang M, Sugimoto M, Ikeda S, Mukai K, Kume S (2014)
Effects of supplemental 兝-cryptoxanthin on IgA-secreting cells in the intestine and mammary glands of lactating mice.

Trace Nutrient Research
31:21-26.


廻堾嫕丒悪杮幚婭丒抮揷弐懢榊丒媣暷怴堦 (2014.11)
斿擕儅僂僗偺堸悈検偲恡婡擻偵媦傏偡墫壔僇儕僂儉媼梌悈弨偺塭嬁

擔杮抺嶻妛夛曬 85:503-507.

Kamano S, Ikeda S, Sugimoto M, Kume S (2014.8)
The effects of calcitonin on the development of and Ca2+ levels in heat-shocked bovine preimplantation embryos in vitro.

J.Reprod.Dev.
60:317-323.


Nagayama T, Sugimoto M, Ikeda S, Kume S (2014.4)
Effects of astaxanthin-enriched yeast on mucosal IgA induction in the jejunum and ileum of weanling mice.

Anim.Sci.J.
85:449-453.


媣暷怴堦 (2014.2)
崟栄榓庬巕媿偺塰梴娗棟偲幘昦梊杊
娭惣抺嶻妛夛曬
171:9-15.


Nishida K, Sugimoto M, Ikeda S, Kume S (2014.1)
Effects of supplemental 兝-carotene on mucosal IgA induction in jejunum and ileum of mice after weaning.

Brit.J.Nutr.
111:247-253.

Ikeda S, Yamada M (2014.2)
Midkine and cytoplasmic maturation of mammalian oocytes in the context of ovarian follicle physiology.

Brit.J.Pharmacol.
171:827-836.

2010
埨徏扟宐巕丒妢堜峗巌丒嶳拞寬屷丒嶁悾廩梞丒惣栰帯丒愒抮彑丒枩強岾婌媣暷怴堦 (2013.8)
弌惗屻偺崟栄榓庬怴惗巕媿傊偺柶塽僌儘僽儕儞G偲柶塽僌儘僽儕儞A偺
堏峴
擔杮抺嶻妛夛曬
84:389-393.


Kume S
(2013)
Evaluation of methane production in high producing cows fed silages during periparturient period.
Advances in Animal Biosciences 4:306.

媣暷怴堦 (2013)
巕媿偺塰梴丒戙幱偺摿堎惈
壠抺姶愼徢妛夛帍2:51-56.


Murai I, Shukuin S, Sugimoto M, Ikeda S, Kume S (2013.6)
Effects of high potassium chloride supplementation on water intake and bodyweight gains in pregnant and lactating mice.
Anim.Sci.J.
84:502-507.

Kuroki T
, Ikeda S, Okada T, Maoka T, Kitamura A, Sugimoto M, Kume S (2013.5)
Astaxanthin ameliorates heat stress-induced impairment of blastocyst development in vitro: -Astaxanthin colocalization with and action on mitochondria-.

J.Assist.Reprod.Genet.
30:623-631.

Wang M, Sugimoto M, Ikeda S, Kume S (2013.4)

Effects of coumestrol administration to maternal mice during pregnancy and lactation on IgA-secreting cells in mammary gland.

Anim.Sci.J.
84:322-327.

2010

Sugimoto M,
Kuwano A, Ikeda S, Kume S, Yoshihara E, Wada S (2012.11)
Investigation of hydration processes of the equine hoof via nuclear magnetic resonance microscopy.
Am.J.Vet.Res. 73: 1775-1780.

Yasumatsuya K, Kasai K, Yamanaka K, Sakase M, Nishino O, Akaike M, Mandokoro K, Nagase T, Kume S (2012.2)
Effects of feeding whey protein on growth rate and mucosal IgA induction in Japanese black calves.
Livestock Science 143:210-213.


Koyama H, Ikeda S, Sugimoto M, Kume S (2012.12)

Effects of folic acid on the development and oxidative stress of mouse embryos exposed to heat stress.
Reprod.Domest.Anim. 47:921-927.

Ikeda S, Koyama H, Sugimoto M, Kume S
(2012.2)
Review: Roles of one-carbon metabolism in preimplantation period亅Effects on short-term development and long-term programming亅
J.Reprod.Dev. 58:38-43.

Ikeda S, Sugimoto M, Kume S
(2012.2)
Importance of methionine metabolism in morula-to-blastocyst transition in bovine preimplantation embryos.
J.Reprod.Dev. 58:91-97.


Ueda M, Horiguchi Y, Sugimoto M, Ikeda S, Kume S
(2012.6)
Effects of coumestrol administration to maternal mice during pregnancy and lactation on renal Ca metabolism in neonatal mice.
Anim.Sci.J. 83:469-473.

Otsuka H, Sugimoto M, Ikeda S, Kume S
(2012.3)
Effects of bisphenol A administration to pregnant mice on serum Ca and intestinal Ca absorption.
Anim.Sci.J. 83:232-237.

Sai T, Matsuda F, Goto Y, Maeda A, Sugimoto M, Gao HM, Kabir AK, Li JY, Manabe N (2012.2)
Effect of RNA interference of BID and BAX mRNAs on apoptosis in granulosa cell-derived KGN cells.
J.Reprod.Dev. 58:112-116.


2010
Kirihata Y, Horiguchi Y, Ueda M, Sugimoto M, Ikeda S, Kume S
(2011.5)
Effects of coumestrol administration to pregnant and lactating mice on intestinal alkaline phosphatase activity.
Phytotherapy Research 25:654-658.


埨徏扟宐巕丒妢堜峗巌丒郷栰婱巎丒惣栰帯丒愒抮彑丒椦摴栫丒媣暷怴堦丒塱悾扖抝 (2011.2)
恖岺傎擕偵偍偗傞戙梡擕偺媼梌検偺曄峏偑崟栄榓庬巕媿偺敪堢偲僗僞乕僞愛庢検偵媦傏偡塭嬁
娭惣抺嶻妛夛曬168:17-23.


Kume S, Sato T, Murai I,
Kitagawa M, Nonaka K, Oshita T (2011.6)
Relationships between urine pH and electrolyte status in cows fed forages.
Anim.Sci.J. 82:456-460.


Nishiyama Y,
Yasumatsuya K, Kasai K, Sakase M, Nishino O, Akaike M, Nagase T, Sugimoto M, Ikeda S, Kume S (2011.5)
Effects of supplemental 兝-carotene with whey on IgA transfer from maternal milk and mucosal IgA induction in neonatal mice and calves.
Livestock Science 137:95-100.


Nishiyama Y, Sugimoto M, Ikeda S, Kume S
(2011.1)
Supplemental 兝-carotene increases IgA secreting cells in mammary gland and IgA transfer from milk to neonatal mice.
British Journal of Nutrition
105:24-30.

Sai T, Goto Y, Yoshioka R, Maeda A, Matsuda F, Sugimoto M, Wongpanit K, Jin HZ, Li JY, Manabe N (2011.6)
Bid and Bax are involved in granulosa cell apoptosis during follicular atresia in porcine ovaries.
J.Reprod.Dev. 57:421-427.


2010
Sugimoto M, Kagawa N, Morita M, Kume S, Wongpanit K, Jin H, Manabe N (2010.8)
Changes in the expression of decoy receptor 3 in granulosa cells during follicular atresia in porcine ovaries.
J.Reprod.Dev. 56:467-474.


崅栘嵷曚巕挿扟愳惔崄抮揷弐懢榊悪杮幚婭媣暷怴堦 (2010.2)
棧擕屻偺儅僂僗偺拏慺棙梡岠棪偍傛傃暢拞IgA偵媦傏偡儂僄乕僞儞僷僋幙偁傞偄偼扙帀擕僞儞僷僋幙媼梌偺塭嬁
娭惣抺嶻妛夛曬166:1-9.

妢堜峗巌丒埨徏扟宐巕丒悾嶳抭攷丒暯峃攷復丒摗扟懽桾丒枩強岾婌丒愒抮彑丒惣栰帯丒媣暷怴堦 (2010.2)
擠怭擕媿傊偺壓棢俆庬崿崌儚僋僠儞偺愙庬偑暘曍屻偺弶擕拞偺柶塽僌儘僽儕儞俧擹搙偍傛傃峈懱壙偵媦傏偡塭嬁

娭惣抺嶻妛夛曬166:27-32.

Namekawa T, Ikeda S, Sugimoto M, Kume S (2010.12)
Effects of astaxanthin-containing oil on development and stress-related gene expression of bovine embryos exposed to heat stress.

Reprod.Domest.Anim. 45:e387-e391.

Ikeda S, Namekawa T, Sugimoto M, Kume S (2010.3)
Expression of methylation pathway enzymes in bovine oocytes and preimplantation embryos.
J.Exp.Zool.A.Ecol.Genet.Physiol. 313:129-136.

Kume S, Nonaka T, Oshita T, Kozakai T (2010.3)
Evaluation of drinking water intake, feed water intake and total water intake in dry and lactating cows fed silages.
Livestock Science 128:46-51.


Murai I, Sugimoto M, Ikeda S, Kume S (2010.2)
Effects of high potassium chloride supplementation on water intake, urine volume and nitrogen balance in mice.

Anim.Sci.J.
81:80-84.

Ikeda S, Sugimoto M, Kume S (2010.4)
Dynamic expression of vimentin in bovine blastocysts in extended in vitro culture.
Reprod.Domest.Anim. 45:295-301.


2009
Tabata Y, Togo D, Kitagawa M, Oishi K, Kumagai H, Kume S, Hirooka Y (2009.8)
Nitrogen, phosphorus, and potassium utilization and their cycling in a beef-forage production system.
Anim.Sci.J. 80:475-485.


Asakura M, Ninomiya S, Sugimoto M, Oku M, Yamashita SI, Okuno T, Sakai Y, Takano Y (2009.4)
Atg26-mediated pexophagy is required for host invasion by the plant pathogenic fungus Colletotrichum orbiculare.

Plant Cell 21:1291-1304.

Ikeda S, Tatemizo A, Iwamoto D, Taniguchi S, Hoshino Y, Amano T, Matsumoto K, Hosoi Y, Iritani A, Saeki K (2009.8)
Enhancement of histone acetylation by trichostatin A during in vitro fertilization of bovine oocytes affects cell number of inner cell mass of the resulting blastocysts.
Zygote 17: 209-215.


2008
惣壀婸旤丒愇捤忳丒埨徏扟宐巕丒媣暷怴堦丒擖峕惓榓 (2008.11)
巗応偵偍偗傞崟栄榓媿偺巬擏扨壙偵媦傏偡奿晅崁栚偍傛傃帀朾
偺棟壔妛揑摿惈偺塭嬁
擔杮抺嶻妛夛曬 79:515-525.

Kume S, Numata K, Takeya Y, Miyagawa Y, Ikeda S, Kitagawa M, Nonaka K, Oshita T, Kozakai T (2008.8)
Evaluation of urinary nitrogen excretion from plasma urea nitrogen in dry and lactating cows.
Asian-Aust.J.Anim.Sci. 21:1159-1163.


Kume S, Nonaka K, Oshita T, Kozakai T, Hirooka H (2008.5)

Effects of urinary excretion of nitrogen, potassium and sodium on urine volume in dairy cows.

Livestock Science 115:28-33
.


Kirihata Y, Kawarabayashi T, Imanishi S, Sugimoto M, Kume S (2008.2)
Coumestrol decreases intestinal alkaline phosphatase activity in post-delivery mice but does not affetct vitamin D receptor and calcium channels in post-delivery and neonatal mice.
J.Reprod.Dev. 54:35-41.


Murai I, Imanishi S, Sugimoto M, Kume S (2008.4)
Effects of high potassium chloride supplementation on growth rate and renal function in mice.
Anim.Sci.J. 79:243-247.


Oshita T, Sudo K, Nonaka K, Kume S, Ochiai K (2008.2)
The effect of feed regimen on chewing time, digesta passage rate and particle size distribution in Holstein non-lactating cows fed pasture ad libitum.
Livestock Science 113:243-250.


2007

Imanishi S, Sugimoto M, Morita M, Kume S, Manabe N (2007.10)
Changes in expression and localization of GPRC5B and RAR兛 in the placenta and yolk sac during middle to late gestation in mice.
J.Reprod.Dev. 53:1131-1136.

Padilla L, Matsui T, Ikeda S, Kitagawa M, Yano H (2007.12)
The effect of vitamin C supplementation on plasma concentration and urinary excretion of vitamin C in cattle.
J.Anim.Sci. 85:3367-3370.

Rodriguez A, Diez C, Caamano JN, de Frutos C, Royo LJ, Munoz M, Ikeda S, Facal N, Alvarez-Viejo M, Gomez E (2007.11)
Retinoid receptor-specific agonists regulate bovine in vitro early embryonic development, differentiation and expression of genes related to cell cycle arrest and apoptosis.
Theriogenology 68:1118-1127
.

Goel S, Sugimoto M, Minami N, Yamada M, Kume S, Imai H (2007.7)
Identification, isolation, and in vitro culture of porcine gonocytes.
Biol.Reprod. 77:123-137.

Oshita T, Takayama H, Otsuka S, Igarashi H, Nonaka K, Kume S (2007.4)
Effects of maturing stage of corn hybrids on silage yield, feeding value for dairy cows and milk production in a cold region of Japan.
Asian-Aust.J.Anim.Sci. 20:511-516.


2006
媣暷怴堦丒挿栰嫗巕丒栘懞堦夒 (2006)
巕媿偺寬峃忬懺丒儈僱儔儖戙幱偵偍傛傏偡僈儔僋僩僆儕僑摐媼梌偺塭嬁.
旝検塰梴慺尋媶 23:22-27.

媣暷怴堦 (2006)
僂僔偺儊僞儞敪惗検偲拏慺偍傛傃儈僱儔儖攔煏検偺惂屼.
抺嶻僔僗僥儉尋媶夛曬 30:25-33.

Chan MP, Morisawa S, Nakayama A, Kawamoto Y, Sugimoto M, Yoneda M (2006)
A physiologically based pharmacokinetic model for endosulfan in the male Sprague-Dawley rats.
Environmental Toxicology 21:464-478.

Ikeda S, Saeki K, Imai H, Yamada M (2006)
Abilities of cumulus and granulosa cells to enhance the developmental competence of bovine oocytes during in vitro maturation period are promoted by midkine; A possible implication of its apoptosis suppressing effects.
Reproduction 132:549-557.

Ikeda S, Prendes JM, Alonso-Montes C, Rodriguez A, Diez C, Kitagawa M, Imai H, Gomez E (2006)
Apoptosis-independent poor morphology of bovine embryos produced by multiple ovulation.
Reprod. Domest. Anim. 41:383-385.

Rodriguez A, Diez C, Ikeda S, Royo LJ, Caamano JN, Alonso-Montes C, Goyache F, Alvarez I, Facal N, Gomez E (2006)
Retinoids during the in vitro transition from bovine morula to blastocyst.
Hum. Reprod. 21:2149-2157.

Gomez E, Diez C, Caamano JN, Goyache F, Royo LJ, Rodriguez A, de Frutos C, Facal N, Ikeda S (2006)
Nuclear receptors, small molecules and reproductive biothechnology.
A
ETE Newsletter
25:11-13.


2005
媣暷怴堦(2005)
崅斿擕媿偺斏怋惉愌夵慞偲塰梴娗棟(1).
壠抺恖岺庴惛 226:24-39.

媣暷怴堦(2005)
崅斿擕媿偺斏怋惉愌夵慞偲塰梴娗棟(2).
壠抺恖岺庼惛 227:40-55.

Kume S, Nonaka K, Oshita T, Kozakai T, Kojima K (2005)
Feeding alfalfa silage on methane production in dry and lactating cows.
Proc. 2nd Greenhouse Gases and Animal Agriculture 428-431.

Kojima H, Kume S, Nonaka K, Oshita T, Kozakai T, Hirooka H (2005)
Effects of feeding and animal performance on nitrogen, phosphorus and potassium excretion by Holstein cows.
Animal Science Journal 76:139-145.

Chan MP, Morisawa S, Nakayama A, Kawamoto Y, Sugimoto M, Yoneda M (2005)
Toxicokinetics of (14)C-endosulfan in male Sprague-Dawley rats following oral administration of single or repeated doses.
Environmental Toxicology 20:533-541.


Nishizawa H, Morita M, Sugimoto M, Imanishi S, Manabe N (2005)
Effects of in utero exposure to bisphenol A on mRNA expression of arylhydrocarbon and retinoid receptors in murine embryos.
J.Reprod.Dev. 51:315-324.

Morita J, Terada Y, Hosoi Y, Fujinami N, Sugimoto M, Nakamura S-I, Murakami T, Yaegashi N, Okamura K (2005)
Microtubule organization during rabbit fertilization by intracytoplasmic sperm injection with and without sperm centrosome.
Reproductive Medicine and Biology 4:169-177.

Uchio-Yamada K, Manabe N, Goto Y, Anann S, Yamamoto Y, Takano K, Ogura A, Matsuda J (2005)
Decreased expression of matrix metalloproteinases and tissue inhibitors of metalloproteinase in the kidneys of hereditary nephrotic (ICGN) mice.
J.Vet.Med.Sci. 67:35-41.

Kagawa N, Sakurai Y, Miyano T, Manabe N (2005)
Effects of long-term grafting on follicular growth in porcine ovarian cortical grafts xenoplanted to severe combined immunodeficient (SCID) mice.
J.Reprod.Dev. 51:77-85.

Kawamoto Y, Matsuyama W, Morikawa M, Morita M, Sugimoto M, Manabe N, Morisawa S (2005)

Disposition of bisphenol A in pregnant mice and fetuses after a single and repeated oral administration.

Toxicol.Environ.Chem. 87:199-213.

Hidalgo C, Diez C, Duque P, Prendes JM, Rodriguez A, Goyache F, Fernandez I, Facal N, Ikeda S, Alonso-Montes C, Gomez E (2005)
Oocytes recovered from cows treated with retinol become unviable as blastocysts produced in vitro.
Reproduction 129:411-421.

Ikeda S, Kitagawa M, Imai H, Yamada M (2005)
The roles of vitamin A in cytoplasmic maturation of bovine oocytes.
J
.Reprod.Dev.
51:23-35.


2004
媣暷怴堦丒栰拞榓媣丒戝壓桭巕丒彫庰堜婱惏丒彫搰塸婭 (2004)
帺媼慹帞椏懡媼帪偵偍偗傞姡擕媿丄擠怭媿偍傛傃斿擕媿偺僇儕僂儉攔煏検.
擔杮抺嶻妛夛曬 75:179-184.

Oshita T, Nonaka K, Kume S, Nakui T (2004)
Effects of forage type on particle size distribution of ruminal digesta and faeces of non-lactating cows fed high quality forage.
Livestock Production Science 91:107-115.


媣暷怴堦丒栰拞榓媣丒戝壓桭巕丒嶳岥捈屓 (2004)
帺媼慹帞椏懡媼帪偵偍偗傞姡擕媿偺堐帩偵梫偡傞戙幱僄僱儖僊乕梫媮検偺悇掕.
擔杮抺嶻妛夛曬 75:31-35.

Kume S, Toharmat T, Ridla M, Nonaka K, Oshita T, Nakamura M, Yamada Y, Ternouth JH (2004)
Effect of high potassium intake from alfalfa silage on mineral status in sheep and periparturient cows.
Res.Bull.Natl.Agric.Res.Cent.for Hokkaido Reg. 181:1-14.

Goto Y, Manabe N, Uchio K, Yamaguchi-Yamada M, Inoue N, Yamamoto Y, Ogura A, Nagano N and Miyamoto H (2004)
Myofibroblastic differentiation in tubulointerstitial cells is provoked by augmented cytoplasmic Smad4 protein in hereditary nephrotic ICGN mice with chronic renal fibrosis.
Cell Tissue Res. 315:209-221.

Uchio-Yamada K, Manabe N, Yamaguchi-Yamada M, Goto Y, Yamamoto Y, Ogura A, Miyamoto H (2004)
Changes in the localization of type I, III and IV collagen mRNAs in the kidneys of hereditary nephritic (ICGN) mice with renal fibrosis.
J.Vet.Med.Sci. 66:123-128.

Yamaguchi-Yamada M, Manabe N, Uchio-Yamada K, Akashi N, Goto Y, Miyamoto Y, Nagao M, Yamamoto Y, Ogura A, Miyamoto H (2004)
Anemia with chronic renal disorder and disrupted metabolism of erythropoietin in ICR-derived glomerulonephritis (ICGN) mice.
J.Vet.Med.Sci. 66:423-431.

Wollenhaupt K, Welter H, Einspanier R, Manabe N, Brussow KP (2004)
Expression of epidermal growth factor receptor (EGF-R), vascular endothelial growth factor receptor (VEGF-R) and fibroblast growth factor receptor (FGF-R) systems in porcine oviduct and endometrium during the time of implantation.
J.Reprod.Dev. 50:269-278.

Yamaguchi-Yamada M, Manabe N, Goto Y, Anan S, Miyamoto K, Miyamoto Y, Nagao M, Yamamoto Y, Ogura A (2004)
Improvement of anemia associated with chronic renal failure by recombinant human erythropoietin treatment in ICR-derived glomerulonephritis (ICGN) mice.
J.Vet.Med.Sci. 66:883-886.

Goto Y, Matsuda-Minehata F, Inoue N, Matsui T, Maeda A, Manabe N (2004)
Porcine (Sus scrofa) cellular FLICE-like inhibitory protein (cFLIP): Molecular cloning and comparison with the human and murine cFLIP.
J.Reprod.Dev. 50:549-555.


2003
Kume S, Nonaka K, Oshita T (2003)
Relationship between parity and mineral status in dairy cows during the periparturient period.
Animal Science Journal 74:211-215.


彫搰塸婭丒峀壀攷擵丒愇揷掕尠丒媣暷怴堦丒搰揷榓岹丒椦岶 (2003)
擕媿偵偍偗傞儕儞攔煏検梊應儌僨儖偺奐敪偲僔儈儏儗乕僔儑儞.
擔杮抺嶻妛夛曬 73:499-507.

Santoso B, Kume S, Nonaka K, Kimura K, Mizukoshi H, Gamo Y, Takahashi J (2003)
Methane emission, nutrient digestibility, energy metabolism and blood metabolites in dairy cows fed silage with and without galacto-oligosaccharides supplementation.
Asian-Aust.J.Anim.Sci. 16:534-540.

Santoso B, Kume S, Nonaka K, Gamo Y, Kimura K, Takahashi J (2003)
Influence of 兝1-4 galacto-oligosaccharides supplementation on nitrogen utilization, rumen fermentation, and microbial nitrogen supply in dairy cows fed silage.
Asian-Aust.J.Anim.Sci. 16:1137-1142.


媣暷怴堦 (2003)丂
擕媿偺斏怋婡擻偺夵慞偲塰梴娗棟.
擔杮泱堏怉妛嶨帍 25:29-37.

媣暷怴堦丒栰拞榓媣丒戝壓桭巕 (2003)丂
姡擕媿偺儊僞儞敪惗検暲傃偵拏慺儈僱儔儖攔煏検偵媦傏偡媼梌慹帞椏偺塭嬁.
杒奀摴擾尋尋曬
178:21-34.

Komatsu K, Manabe N, Kiso M, Shimabe M, Miyamoto H (2003)
Changes in localization of immune cells and cytokines in corpora lutea during luteolysis in murine ovaries.
J.Exp.Zool. 296:152-159.

Komatsu K, Manabe N, Kiso M, Shimabe M, Miyamoto H (2003)
Soluble Fas (FasB) regulates luteal cell apoptosis during luteolysis in murine ovaries.
Mol.Reprod.Dev. 65:345-352.

Matsui T, Manabe N, Goto Y, Inoue N, Nishihara S, Miyamoto H (2003)
Changes in the expression and activity of caspase-9 and Apaf1 in granulosa cells during follicular atresia in pig ovaries.
Reproduction 126:113-120.

Egerszegi I, Schneider F, R_tky J, So_s F, Solti L, Manabe N, Br_ssow KP (2003)
Comparison of luteinizing hormone and steroid hormone secretion during the peri- and post-ovulatory periods in mangalica and landrace gilts.
J.Reprod.Dev. 49:291-296.

Inoue N, Manabe N, Matsui T, Maeda A, Nakagawa S, Wada S, Miyamoto H (2003)
Roles of tumor necrosis factor-related apoptosis-inducing ligand signaling pathway in granulosa cell apoptosis during atresia in pig ovaries.
J.Reprod.Dev. 49:313-321.

Imanishi S, Manabe N, Nishizawa H, Morita M, Sugimoto M, Iwahori M, Miyamoto H (2003)
Effects of oral exposure of bisphenol A on mRNA expression of nuclear receptors in murine placentae assessed by DNA microarray.
J.Reprod.Dev. 49:329-336.

Izumi T, Sakakida S, Nagai T, Miyamoto H (2003)
Allometric study on the relation between the growth of preantral and antral follicles and that of oocytes in bovine ovaries.
J.Reprod.Dev. 49:361-368.


嶅揷惎巎丄愹摽榓丄徏杮梉壚丄戝惣婎巕丄惣愳抦巕丄媨杮尦 (2003)
僂僔棏憙偐傜600兪m 枹枮偺棏朎偲棏曣嵶朎懳偺暘棧曽朄偑夞廂棪偵媦傏偡塭嬁
擔杮泱堏怉妛嶨帍 25:113-120.

Kiso M, Manabe M, Komatsu K, Shimabe M, Miyamoto H (2003)
Abnormal structural luteolysis in ovaries of the senescence accelerated mouse (SAM): expression of Fas Ligand/Fas-mediated apoptosis signaling molecules in luteal cells.
J.Reprod.Dev. 49:457-463.

Nishizawa H, Manabe N, Morita M, Sugimoto M, Miyamoto H (2003)
Effects of in utero exposure of bisphenol A on expression of RXR兛 and RAR兛 mRNAs in murine embryos.
J.Reprod.Dev. 49:539-45.


悪杮幚婭丄崃撶徃丄媨杮尦 (2003)
棏憙慻怐偺搥寢曐懚
堛妛偺偁備傒 204: 921-925.

Ikeda S, Imai H, Yamada M (2003)
Apoptosis in cumulus cells during in vitro maturation of bovine cumulus-enclosed oocytes.
Reproduction 125:369-376.


2002
戝壓桭巕丒栰拞榓媣丒媣暷怴堦丒娾熀丂宑丒変桳丂枮 (2002)
僈儗僈僒僀儗乕僕偺帞椏惉暘慻惉丄敪峺昳幙偍傛傃塰梴壙.
擔杮憪抧妛夛帍 48:428-432.

拞懞惓搇丒嵅摗媊榓丒栴梡寬堦丒嶳揷丂朙丒嶁岥丂幚丒媣暷怴堦 (2002)
暘曍慜偐傜偺傾儖僼傽儖僼傽僒僀儗乕僕偺媼梌偑擕擬敪惗丄嵦怘検偍傛傃擕惗嶻偵媦傏偡塭嬁.
杒奀摴抺嶻妛夛曬 44:29-37.

Kume S (2002)
Establishment of profitable dairy farming system on control of methane production in Hokkaido region.
Greenhouse Gases and Animal Agriculture. 87-94. Elsevier Science Ltd.

Wada S, Manabe N, Inoue N, Nakayama M, Matsui T, Miyamoto H (2002)
TRAIL-decoy receptor-1 disappears in granulosa cells of atretic follicles in porcine ovaries.
J.Reprod.Dev. 48:167-173.

Wada S, Manabe N, Inoue N, Nakayama M, Matsui T, Miyamoto H (2002)
TRADD is involved in apoptosis induction in granulosa cells during atresia in pig ovaries.
J.Reprod.Dev. 48:175-181.

Sugimoto M, Manabe N, Morita M, Tanaka T, Okamoto R, Imanishi S, Miyamoto H (2002)
Availability of NMR microscopic observation of mouse embryo disorder: Examination in malformations induced by maternal administration of retinoic acid.
J.Vet.Med.Sci. 64:427-433.

Wada S, Manabe N, Nakayama M, Inoue N, Matsui T, Miyamoto H (2002)
TRAIL-decoy receptor 1 plays inhibitory role in apoptosis of granulosa cells from pig ovarian follicles.
J.Vet.Med.Sci. 64:435-439.

Uchio K, Tuchweber B, Manabe N, Gabbiani G, Rosenbaum J, Desmouliere A (2002)
Cellular retinol-binding protein-1 expression and modulation during in vivo and in vitro myofibroblastic differentiation of rat hepatic stellate cells and portal fibroblasts.
Lab.Invest. 82:619-628.


2001
Kume S, Toharmat T (2001)
Effect of colostral 兝-carotene and vitamin A on vitamin and health status of newborn calves.
Livestock Production Science 68:61-65.

Kume S, Toharmat T, Nonaka K, Oshita T, Nakui T, Ternouth JH (2001)

Relationships between crude protein and mineral concentrations in alfalfa and value of alfalfa silage as a mineral source for periparturient cows.

Animal Feed Science and Technology 93:157-168.

Kume S, Toharmat T (2001)
Electrolyte status and fecal consistency in newborn calves.
Asian-Aust.J.Anim.Sci. 14:640-645.


栰拞榓媣丒媣暷怴堦丒戝壓桭巕 (2001)
杸嵱張棟偑掅悈暘僒僀儗乕僕偺in sacco徚壔棪暲傃偵徚壔惈偵媦傏偡塭嬁.
擔杮憪抧妛夛帍 47:405-411.

媣暷怴堦丒柤媣堜拤丒栰拞榓媣丒戝壓桭巕 (2001)
傾儖僼傽儖僼傽偺惗堢偵傛傞塰梴壙偺曄摦.
杒擾
68:8-14.

Kume S, Okamoto T, Sasaki O, Uetake K, Yayou K, Ternouth JH (2001)
Effect of calving season and parity on milk yield and milk composition of high producing cows in Hokkaido.
Res.Bull.Hokkaido.Natl.Agric.Exp.Stn. 173:37-45.

Uchio-Yamada K, Manabe N, Yamaguchi M, Akashi N, Goto Y, Yamamoto Y, Ogura A, Miyamoto H (2001)
Localization of extracellular matrix receptors in ICGN mice, a strain of mice with hereditary nephrotic syndrome.
J.Vet.Med.Sci. 63:1171-1178.

Yamaguchi M, Manabe N, Uchio-Yamada K, Akashi N, Yamamo Y, Ogura A, Miyamoto H (2001)
Localization of proliferative and apoptotic cells in the kidneys of ICR-derived glomerulonephritis (ICGN) mice.
J.Vet.Med.Sci. 63:781-787.

Manabe N, Kinoshita A, Yamaguchi M, Furuya Y, Nagano N, Yamada-Uchio K, Akashi N, Miyamoto-Kuramitsu K, Miyamoto, H (2001)
Changes in quantitative profile of extracellular matrix components in the kidneys of rats with adriamycin-induced nephropathy.
J.Vet.Med.Sci. 63:125-133.